DRW, Wintermute and IMC build prediction-market trading desks for Polymarket, Kalshi

Major quantitative trading firms including DRW, Wintermute and IMC are building dedicated desks to trade prediction markets such as Polymarket and Kalshi, focusing on arbitrage and market microstructure rather than forecasting event outcomes, according to CoinDesk. DRW job listings cite sub-second cross-platform and news-driven strategies. Polymarket processed between $22 billion and $40 billion in 2025, with sports markets including $256 million on UEFA Champions League Winner, $399 million on 2026 NBA Champion and $79 million on 2026 NHL Stanley Cup. HyperLiquid is preparing to launch prediction markets ahead of the 2026 World Cup.